Reaching a medical diagnosis in the shortest possible time is the goal of advanced medicine. The identification and characterization of the genome is a reality. This allows us to reach the frontier of science in a revolutionary way. The state of health depends on the genome, but the environment, microbiome and habits that the human being practices, induce the chemical/protein changes that signal the gene what to do. The application in cancer has been a paradigm shift and genetic engineering is now a reality that has broadened the horizon of our medical practice and healthy aging. The 'epigenetic' profile allows to adjust the ability to predict diseases, early diagnosis and define aging.
Is aging a preventable disease? The target is low-grade inflammation.
In the centenary of the discovery of insulin we emphasize that with its discovery, we have changed diabetes from an acute lethal disease to a chronic disease. Throughout these years we have associated it with obesity. This new pandemic is the cause of premature aging and shortening of life expectancy. Its prevention would drag like dominoes the diseases associated with unhealthy aging.
The development of modern anti-diabetic treatments has shifted its target 'glycemia' to the protection of the organs that the pandemic affects. This has revolutionized clinical practice. Cardiology and nephrology are in this case the most benefited by offering anti-diabetic treatments as the first line of treatment of renal and cardiological diseases. Scientific evidence indicates that gut bacteria can talk to the brain and are part of the epigenetic expression particularly in Obesity/Diabetes.
On its 40th anniversary we not only celebrate that we have tools that prevent virus replication, thereby decreasing inflammation levels, but also that advances in prevention with prophylaxis and pre-exposure tools offer guarantees for at-risk groups.
A new scenario emerges as a reality for patients suffering from the disease, offering a long healthy life with new treatments.
What is most fascinating is that as we contemplate the future, we see that it verges on the dream of AIDS eradication with new treatments and a vaccine.